A Turbo Detection and Sphere-Packing-Modulation-Aided Space-Time Coding Scheme

Arecently proposed space-time block-coding (STBC) signal-construction method that combines orthogonal design with sphere packing (SP), referred to here as STBC-SP, has shown useful performance improvements over Alamouti’s conventional orthogonal design. In this contribution, we demonstrate that the performance of STBC-SP systems can be further improved by concatenating SP-aided modulation with channel coding and performing demapping as well as channel decoding iteratively. We also investigate the convergence behavior of this concatenated scheme with the aid of extrinsic-information-transfer charts. The proposed turbo-detected STBC-SP scheme exhibits a “turbo-cliff” at Eb/N0 = 2.5 dB and provides Eb/N0 gains of approximately 20.2 and 2.0 dB at a bit error rate of 10?5 over an equivalent throughput uncoded STBC-SP scheme and a turbo-detected quadrature phase shift keying (QPSK) modulated STBC scheme, respectively, when communicating over a correlated Rayleigh fading channel. Index Terms—EXIT charts, iterative demapping, multidimensional mapping, space-time coding, sphere packing, turbo detection

Turbo Detection of Space-time Trellis-Coded Constant Bit Rate Vector-Quantised Videophone System using Reversible Variable-Length Codes, Convolutional Codes and Turbo Codes

In this treatise we characterise the achievable performance of a proprietary video transmission system, which employs a Constant Bit Rate (CBR) video codec that is concatenated with one of three error correction codecs, namely a Reversible Variable-Length Code (RVLC), a Convolutional Code (CC) or a convolutional-based Turbo Code (TC). In our investigations, the CBR video codec was invoked in conjunction with Space-Time Trellis Coding (STTC) designed for transmission over a dispersive Rayleigh fading channel. At the receiver, the channel equaliser, the STTC decoder and the RVLC, CC or TC decoder, as appropriate, employ the Max-Log Maximum A-Posteriori (MAP) algorithm and their operations are performed in an iterative 'turbo-detection' fashion. The systems were designed for maintaining similar error-free video reconstruction qualities, which were found to be subjectively pleasing at a Peak Signal to Noise Ratio (PSNR) of 30.6~dB, at a similar decoding complexity per decoding iteration. These design criteria were achieved by employing differing transmission rates, with the CC- and TC-based systems having a 22% higher bandwidth requirement. The results demonstrated that the TC-, RVLC- and CC-based systems achieve acceptable subjective reconstructed video quality associated with an average PSNR in excess of 30~dB for $E_b/N_0$ values above 4.6~dB, 6.4~dB and 7.7~dB, respectively. The design choice between the TC- and RVLC-based systems constitutes a trade-off between the increased error resilience of the TC-based scheme and the reduced bandwidth requirement of the RVLC-based scheme

Retrofitting Crude Oil Refinery Heat Exchanger Networks to Minimise Fouling While Maximising Heat Recovery

The use of fouling factors in heat exchanger design and the lack of appreciation of fouling in traditional pinch approach has often resulted badly designed crude preheat networks that are expensive to maintain. The development of thermal and pressure drop models for crude oil fouling has allowed its effects to be quantified, so that techno-economic analyses can be performed and various design options compared. Application of these fouling models is carried out on two levels: on the assessment of adding extra area to individual exchangers, and the design of a complete network using the Modified Temperature Field Plot. Application to a refinery case study showed that both at the exchanger and network levels, designing for maximum heat recovery using traditional pinch approach results in the least efficient heat recovery over a time period when fouling occurs

Prevalence of macropod progressive periodontal disease ("lumpy jaw") in wild western grey kangaroos (Macropus fuliginosus)

Macropod Progressive Periodontal Disease (MPPD), colloquially referred to as “lumpy jaw”, is a commonly observed disease in captive macropods. However, the prevalence of this disease in the wild is largely unknown. A systematic study of MPPD in wild macropods would provide an indication of the endemic presence of this disease in wild populations, and could assist those managing disease in captive populations, by highlighting potential risk factors for disease development. Utilising kangaroos culled as part of a population management program, this study used visual observation and computer tomography (CT) of skulls to investigate the prevalence of MPPD in wild western grey kangaroos (Macropus fuliginosus) from the Perth metropolitan region, Western Australia. The sample suitable for visual and CT analysis comprised 121 specimens, 71 (58.7%) male and 50 (41.3%) female, with the mean age for all 121 specimens being 4.5 years (±2.63 SD). No evidence of MPPD was detected in any of the specimens examined. Overabundance may not be associated with the development of MPPD, as previously considered, and age-related factors should not be eliminated. This results may reflect low susceptibility to MPPD in western grey kangaroos, given low prevalence is reported in this species in captive populations. Further investigation into species-specificity is recommended, and should include samples with soft tissue to improve sensitivity of disease detection. Surveillance of MPPD in wild populations of macropods helps to improve our understanding of the biological significance, development and potential spread of this disease. Notably, this information may assist in the management of MPPD in captive populations, and may have a positive impact on both the welfare and conservation of macropods in captivity

Bone Turnover Markers Including Undercarboxylated Osteocalcin Are Associated With Mortality Risk in Older Men

Osteocalcin in its undercarboxylated form (ucOC) may influence diabetes risk; however, its relationship with all-cause and cause-specific mortality is unclear. Whether other bone turnover markers (BTMs) are associated with mortality risk differently from ucOC also remains uncertain. Our aim was to determine associations of serum ucOC with all-cause and cause-specific mortality and compare these with the corresponding associations of serum total osteocalcin (TOC), procollagen type I N-propeptide (PINP), and collagen type 1 C-terminal cross-linked telopeptide (CTX) in older men. We conducted a prospective cohort study of 3871 community-dwelling men, aged 77.0 ± 3.6 years at baseline, followed for a median of 12.3 years. Exposure variables were ucOC, TOC, PINP, and CTX concentrations assayed in serum. Outcomes were incidence of all deaths and deaths due to cardiovascular disease (CVD) or cancer, ascertained using death registry data. Cox regression analyses adjusted for cardiovascular risk factors and prevalent CVD and for prevalent cancer in analyses of cancer-related mortality. Higher concentrations of ucOC, PINP, and CTX were associated with all-cause mortality (hazard ratio [HR] per 1 standard deviation increase: ucOC 1.12, 95% confidence interval [CI] 1.06–1.18, p < 0.001; PINP HR = 1.06, 95% CI 1.01–1.11, p = 0.009; CTX HR = 1.13, 95% CI 1.08–1.19, p < 0.001), but TOC was not associated. Similar results were found after excluding men with an incident fracture during follow-up. Higher ucOC and CTX were associated with CVD mortality (ucOC HR per 1 SD increase 1.13, 95% CI 1.05–1.22, p = 0.001; CTX HR = 1.12, 95% CI 1.04–1.20, p = 0.003), but this result was not significant in competing risks analysis. Higher CTX was also associated with cancer mortality (HR = 1.12, 95% CI 1.01–1.23, p = 0.024). In conclusion, in older men, higher bone turnover, assessed by BTMs including ucOC, is a biomarker for all-cause mortality risk. Undercarboxylated osteocalcin was a more informative biomarker for this outcome than TOC. Higher CTX was associated with all-cause and cancer-related mortality. Further evaluation of causality and potential underlying mechanisms is warranted. © 2022 The Authors. Journal of Bone and Mineral Research published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research (ASBMR)

Statistical Mechanics Analysis of LDPC Coding in MIMO Gaussian Channels

Using analytical methods of statistical mechanics, we analyse the typical behaviour of a multiple-input multiple-output (MIMO) Gaussian channel with binary inputs under LDPC network coding and joint decoding. The saddle point equations for the replica symmetric solution are found in particular realizations of this channel, including a small and large number of transmitters and receivers. In particular, we examine the cases of a single transmitter, a single receiver and the symmetric and asymmetric interference channels. Both dynamical and thermodynamical transitions from the ferromagnetic solution of perfect decoding to a non-ferromagnetic solution are identified for the cases considered, marking the practical and theoretical limits of the system under the current coding scheme. Numerical results are provided, showing the typical level of improvement/deterioration achieved with respect to the single transmitter/receiver result, for the various cases.Comment: 25 pages, 7 figure

A retrospective study of macropod progressive periodontal disease ("lumpy jaw") in captive macropods across Australia and Europe: using data from the past to inform future macropod management

Macropod Progressive Periodontal Disease (MPPD) is a well-recognised disease that causes high morbidity and mortality in captive macropods worldwide. Epidemiological data on MMPD are limited, although multiple risk factors associated with a captive environment appear to contribute to the development of clinical disease. The identification of risk factors associated with MPPD would assist with the development of preventive management strategies, potentially reducing mortality. Veterinary and husbandry records from eight institutions across Australia and Europe were analysed in a retrospective cohort study (1995 to 2016), examining risk factors for the development of MPPD. A review of records for 2759 macropods found incidence rates (IR) and risk of infection differed between geographic regions and individual institutions. The risk of developing MPPD increased with age, particularly for macropods >10 years (Australia Incidence Rate Ratio (IRR) 7.63, p < 0.001; Europe IRR 7.38, p < 0.001). Prognosis was typically poor, with 62.5% mortality reported for Australian and European regions combined. Practical recommendations to reduce disease risk have been developed, which will assist zoos in providing optimal long-term health management for captive macropods and, subsequently, have a positive impact on both the welfare and conservation of macropods housed in zoos globally

Conventional approach to harmonious coordinated Cadastral Database weakness

The eKadaster system depended solely on the use of coordinated cadastral database known as the National Digital Cadastral Database (NDCDB) with an expected accuracy of ±10cm. Till date, there is an approximately of 7.8 million land parcels and 21.9 million boundary markers in the NDCDB that covers the total area of 132,183 km2. However, the NDCDB accuracy of ±10cm is still not at a satisfactory acceptance level and the adjustment keeps continuing without carrying out verification to the data sources weakness of varying accuracy and input errors. Thus, the foremost important corrective is to ensure the adjustment input files to have the exact value of the sources by further divided the existing adjustment blocks into smaller blocks to verify the input data line by line. A well distributed cadastral control points and latest NDCDB accessibility are also extensively needed to plan and to strengthen the adjustment network. The comparison result of the randomly picked ground truthing points in the field has shown a significant impact on the displacement accuracy that meet the expected tolerance of ±10cm or better after the data input file is cleaned without input error. And to further strengthen the adjustment network in order to make NDCDB accuracy better, the current cadastral control points shall need to tie to a highest accuracy fundamental network

Post-transcriptional regulation of androgen receptor mRNA by an ErbB3 binding protein 1 in prostate cancer

Androgen receptor (AR)-mediated pathways play a critical role in the development and progression of prostate cancer. However, little is known about the regulation of AR mRNA stability and translation, two central processes that control AR expression. The ErbB3 binding protein 1 (EBP1), an AR corepressor, negatively regulates crosstalk between ErbB3 ligand heregulin (HRG)-triggered signaling and the AR axis, affecting biological properties of prostate cancer cells. EBP1 protein expression is also decreased in clinical prostate cancer. We previously demonstrated that EBP1 overexpression results in decreased AR protein levels by affecting AR promoter activity. However, EBP1 has recently been demonstrated to be an RNA binding protein. We therefore examined the ability of EBP1 to regulate AR post-transcriptionally. Here we show that EBP1 promoted AR mRNA decay through physical interaction with a conserved UC-rich motif within the 3′-UTR of AR. The ability of EBP1 to accelerate AR mRNA decay was further enhanced by HRG treatment. EBP1 also bound to a CAG-formed stem-loop in the 5′ coding region of AR mRNA and was able to inhibit AR translation. Thus, decreases of EBP1 in prostate cancer could be important for the post-transcriptional up-regulation of AR contributing to aberrant AR expression and disease progression